System and method for focusing of high intensity focused ultrasound based on magnetic resonance—acoustic radiation force imaging feedback
US9119955B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 23, 2013 |
| Grant date | Sep 1, 2015 |
| Priority date | — |
| Expiry date | Nov 22, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2007/0086
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A system and method for focusing ultrasound into a target tissue is disclosed. The method calculates a pressure field for an array of transducer elements to generate an unaberrated pressure field matrix and causes the transducer elements to apply focused ultrasound to generate a respective aberrated pressure field at a focus location in a target tissue and surrounding volume. MR-ARFI images are acquired of the focus location and surrounding volume, a magnitude of the aberrated pressure field is measured that is generated by the applied focused ultrasound at respective focus locations in the target tissue and surrounding volume based on the MR-ARFI images, an aberration for the transducer elements is determined from the pressure field matrix and the MR-ARFI images of the focus location and the surrounding volume using a magnitude least-squares method, and a corrective phase/amplitude adjustment is applied to the transducer elements based on the determined aberrations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.