Triazine carboxamides as sodium channel blockers
US9120786B2 · kind B2 · utility
26Cited by
21References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 26, 2014 |
| Grant date | Sep 1, 2015 |
| Priority date | — |
| Expiry date | Feb 26, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present disclosure provides substituted triazine carboxamides of Formula I:and the pharmaceutically acceptable salts and solvates thereof, wherein A1, X, A2, E, and Z are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present disclosure are especially useful for treating pain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.