Metal complexes of poly(carboxyl)amine-containing ligands having an affinity for carbonic anhydrase IX
US9120837B2 · kind B2 · utility
5Cited by
22References
31Claims
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Key dates
| Filing date | Jan 4, 2013 |
| Grant date | Sep 1, 2015 |
| Priority date | — |
| Expiry date | Jan 4, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D233/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to CA IX inhibitors that conform to Formula I where the substituents X, A, B, D, E, E′ and G are as defined above.Also described are Pt, 64Cu, 186Re, 188Re and 99mTc metal complexes of Formula I compounds which find use as candidate agents for imaging tumors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.