Method for the preparation of diols
US9121041B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 27, 2011 |
| Grant date | Sep 1, 2015 |
| Priority date | — |
| Expiry date | Sep 23, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/04
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention concerns a new method for the biological preparation of a diol comprising culturing a microorganism genetically modified for the bioproduction of an aliphatic diol, wherein the microorganism comprises a metabolic pathway for the decarboxylation of a hydroxy-2-keto-aliphatic acid metabolite with an enzyme having a 2-keto acid decarboxylase activity, the product obtained from said decarboxylation step being further reduced into the corresponding aliphatic diol, and wherein the microorganism is genetically modified for the improved production of said hydroxy-2-keto-aliphatic acid metabolite.The invention also concerns a modified microorganism for the production of an aliphatic diol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.