Patent · US Active

Nanopore sequencing using n-mers

US9121064B2 · kind B2 · utility

8Cited by

13References

18Claims

0Family size

Assignee

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. · US

Inventors

Stephen Turner · Menlo Park, US
Benjamin Flusberg · Atlanta, US

Key dates

Filing date	Feb 10, 2015
Grant date	Sep 1, 2015
Priority date	—
Expiry date	Feb 10, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2565/631
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention relates to devices and methods for nanopore sequencing. The invention provides for using the signals from n-mers to provide sequence information, for example where the system has less than single base resolution. The invention includes arrays of nanopores having incorporated electronic circuits, for example, in CMOS. In some cases, the arrays of nanopores comprise resistive openings for isolating the electronic signals for improved sequencing. Methods for controlling translocation of through the nanopore are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.