Hetero-bicyclic derivatives as HCV inhibitors

US9126986B2 · kind B2 · utility

Assignee

• Janssen Sciences Ireland UC · IE

Inventors

• Koen Vandyck · Beringen, BE
• Wim Gaston Verschueren · Berchem, BE
• Pierre Jean-Marie Bernard Raboisson · Sligo, IE

Key dates

• Filing date: Dec 27, 2012
• Grant date: Sep 8, 2015
• Expiry date: Dec 27, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/113
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Inhibitors of HCV replication of formula I, including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein R and R′ have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HCV inhibitors, in HCV therapy.