Patent · US Active

Glucosylceramide synthase inhibitors

US9126993B2 · kind B2 · utility

4Cited by

11References

1Claims

0Family size

Assignee

Genzyme Corporation · US

Inventors

Elyse Bourque · Langley, CA
Bradford H. Hirth · Framingham, US
Renato Sklerj · Newton, US
Elina Makino · Winchester, US
Fazeela MORSHED · Waltham, US
Lingyun Li · Waltham, US
Paul Mason · Natick, US
John Leonard · Manchester, US
James Lillie · Wellesley, US
Hanlan Liu · New City, US
Mary A. CROMWELL · Groton, US
Bing Wang · San Jose, US
Thomas O'SHEA · Wellesley, US

Key dates

Filing date	Aug 28, 2014
Grant date	Sep 8, 2015
Priority date	—
Expiry date	Aug 28, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y302/01022
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.