Cyclic depsipeptides

US9127044B2 · kind B2 · utility

Assignee

• Novartis AG · CH

Inventors

• Philipp Krastel · Weil am Rhein, DE
• Brigitta-Maria Liechty · Basel, CH
• Josef Gottfried Meingassner · Wien, AT
• Esther Schmitt · Bad Kötzting, DE
• Erwin Schreiner · Wien, AT

Key dates

• Filing date: Feb 14, 2012
• Grant date: Sep 8, 2015
• Expiry date: Jun 6, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to cyclic depsipeptides, or derivatives thereof, having the structure of formula (I), and uses thereof, e.g. as inhibitors of kallikrein 7 and human neutrophil elastase.