Tissue and organ graft bioreactor and method of operation

US9127242B2 · kind B2 · utility

Inventors

• Patrick Guertin · Mendon, US
• Parrish M. Galliher · Littleton, US
• Michael Fisher · Ashland, US
• Joseph D. Crowell · Hamilton, US
• Colin R. Tuohey · Marlborough, US
• Laura A. Niklason · Greenwich, US
• William E. Tente · Seekonk, US
• Shannon M. Dahl · Durham, US
• Juliana Blum · Wake Forest, US
• Justin T. Strader · Cary, US

Key dates

• Filing date: Apr 5, 2010
• Grant date: Sep 8, 2015
• Expiry date: Apr 5, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12M29/06
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A single-use, single or multiple tissue, organ, and graft bioreactor and environmental control system is designed to replicate the necessary conditions for growth of tissues, organs, or grafts, while addressing problems in scaling up the tissue growth; adaptation to a single-use or disposable format; and operation as a stand-alone unit that provides full environmental control of cell culture conditions.