Scaffolding for tissue regeneration or repair
US9127254B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 13, 2007 |
| Grant date | Sep 8, 2015 |
| Priority date | — |
| Expiry date | Oct 8, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/74
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention relates to bioresorbable scaffolding for tissue regeneration or repair. The present invention describes an epithelial organoid comprising an aggregate of epithelial cells predominantly expressing markers associated with differentiated cell types, and an aggregate which assumes a structure or performs a function associated with an epithelial organ or a fragment thereof. The present invention also provides a method of treating a subject in need of repair or replacement of an organ or a portion thereof; and/or a method of treating a subject with a disease or disorder which impairs or abrogates a liver, kidney, pancreas, thyroid or pituitary function. The present invention also describes an epithelial graft or artificial organ comprising spheroids, organoids or a combination thereof, and a kit for implantable epithelial graft formation comprising organoids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.