Patent · US Active

Metabolically enhanced cyanobacterial cell for the production of ethanol

US9127297B2 · kind B2 · utility

4Cited by

13References

24Claims

0Family size

Assignee

Algenol Biotech LLC · US

Inventors

Ulf Dühring · Fredersdorf, DE
Heike Enke · Berlin, DE
Karl Ziegler · Zeuthen, DE
Torsten Schwecke · Berlin, DE

Key dates

Filing date	Jun 16, 2014
Grant date	Sep 8, 2015
Priority date	—
Expiry date	Jun 16, 2034

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/52
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A metabolically enhanced cyanobacterial cell for the production of ethanol is provided. The metabolically enhanced cyanobacterial cell for the production of ethanol comprises at least one recombinant gene encoding a pyruvate decarboxylase enzyme (Pdc) converting pyruvate to acetaldehyde, and at least one recombinant gene encoding a first Zn2+ dependent alcohol dehydrogenase enzyme (Adh) converting acetaldehyde to ethanol. The invention also provides a method for producing the metabolically enhanced cyanobacterium, a method for producing ethanol with the metabolically enhanced cyanobacterium, and a method for screening of alcohol dehydrogenase enzyme expressing cyanobacterial strains for the presence of NADPH-dependent native alcohol dehydrogenase enzymes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.