Patent · US Active

Labelled nucleotides

US9127314B2 · kind B2 · utility

17Cited by
89References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 6, 2013
Grant dateSep 8, 2015
Priority date
Expiry dateNov 6, 2033

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/143333
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention provides a nucleotide or nucleoside having a base attached to a detectable label via a cleavable linker, characterized in that the cleavable linker contains a moiety selected from the group comprising: Formula (I) (wherein X is selected from the group comprising O, S, NH, and NQ wherein Q is a C1-10 substituted or unsubstituted alkyl group, Y is selected from the group comprising O, S, NH, and N(allyl), T is hydrogen or a C1-10 substituted or unsubstituted alkyl group and * indicates where the moiety is connected to the remainder of the nucleotide or nucleoside).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.