Multiplexed KRAS mutation detection assay
US9127318B2 · kind B2 · utility
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22Claims
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Key dates
| Filing date | Aug 24, 2012 |
| Grant date | Sep 8, 2015 |
| Priority date | — |
| Expiry date | Aug 23, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/16
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein is reagent mixture comprising multiplexed amplification reagents and flap assay reagents for detecting, in a single reaction, mutant copies of the KRAS gene that contain any of the 34A, 34C, 34T, 35A, 35C, 35T or 38A point mutations. Methods that employ the reagent mix and kits for performing the same are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.