Focused radiation for augmenting immune-based therapies against neoplasms
US9132281B2 · kind B2 · utility
56Cited by
1References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 19, 2012 |
| Grant date | Sep 15, 2015 |
| Priority date | — |
| Expiry date | Jun 19, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2300/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An approach combining immune-based therapies with focused radiation, including stereotactic radiation, to treat cancers is disclosed. The use of focused radiation primes the immune system in a similar manner to vaccines to augment immune-based therapies and can counteract the suppressive effects of a tumor. The combination of focused radiation and immune-based therapies, including administration of at least one immunotherapeutic agent, improves survival compared to each therapy alone and can, in some cases, lead to a durable cure. Accordingly, focused radiation can be an adjuvant for immune-based therapies for treating cancers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.