Patent · US Active

Triple reuptake inhibitors and methods of their use

US9133117B2 · kind B2 · utility

2Cited by
3References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 24, 2013
Grant dateSep 15, 2015
Priority date
Expiry dateOct 24, 2033

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D209/52
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein are bicyclic compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders. Compounds provided herein inhibit reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine (e.g., from the synaptic cleft) and modulate one or more monoamine transporter. Pharmaceutical formulations containing the compounds are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.