Patent · US Active

Fentanyl derivatives as pH-dependent opioid receptor agonists

US9133120B2 · kind B2 · utility

0Cited by

2References

9Claims

0Family size

Assignees

CHARITÉ—UNIVERSITÄTSMEDIZIN BERLIN · DE
KONRAD-ZUSE-INSTITUT · DE

Inventors

Christoph Stein · Baltimore, US
Marcus Weber · Berlin, DE
Christian J. Zollner · Goleta, US
Olga Scharkoi · Berlin, DE

Key dates

Filing date	Aug 17, 2012
Grant date	Sep 15, 2015
Priority date	—
Expiry date	Aug 17, 2032

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention relates to fluorinated fentanyl derivatives that function as opioid receptor agonists, which activate target opioid receptors in a pH-dependent manner, and are thus selective for the receptors in inflamed (acidic) milieu; uses thereof and pharmaceutical compositions comprising them.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.