Amide compounds, compositions and uses thereof

US9133122B2 · kind B2 · utility

Assignee

• EVOTEC AG · DE

Inventors

• Zhi-Liang Wei · South San Francisco, US
• Sumithra Gowlugari · San Mateo, US
• Carl Kaub · San Jose, US
• Zhan Wang · San Jose, US
• Yeyu Cao · Austin, US
• John Kincaid · Hayward, US

Key dates

• Filing date: Jul 9, 2014
• Grant date: Sep 15, 2015
• Expiry date: Jul 9, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds are provided according to formula 1:where A, B, W, X′, L, R1, R3, R4b, and m′ are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others.