Patent · US Active

Methods of use of inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme

US9133145B2 · kind B2 · utility

0Cited by

19References

19Claims

0Family size

Assignee

Abb Vie Inc. · US

Inventors

R. Scott Bitner · Pleasant Prairie, US
Kaitlin E. Browman · Deerfield, US
Michael E. Brune · Mundelein, US
Steven Fung · Palo Alto, US
Peer B. Jacobson · Libertyville, US
Lynne E. Rueter · Round Lake Beach, US
Marina I. Strakhova · Vernon Hills, US
Jiahong Wang · Northbrook, US
James T. Link · Stanford, US
Yixian Chen · Park City, US
Hwan-Soo Jae · Glencoe, US
Jyoti R. Patel · Libertyville, US
Marina Pliushchev · Vernon Hills, US
Jeffrey J. Rohde · Evanston, US
Qi Shuai · DeKalb, US
Bryan K. Sorensen · Antioch, US
Martin Winn · Deerfield, US
Dariusz Wodka · Waukegan, US
Hong Yong · Libertyville, US

Key dates

Filing date	Mar 1, 2013
Grant date	Sep 15, 2015
Priority date	—
Expiry date	Mar 1, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D491/056
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.