Aurora and FLT3 kinases modulators
US9133180B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Feb 4, 2013 |
| Grant date | Sep 15, 2015 |
| Priority date | — |
| Expiry date | Feb 4, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a compound having the formula (1):and salts thereof; wherein:R1 is hydrogen or C1-2 alkyl; andR2, R3 and R4 are the same or different and each is selected from hydrogen, C1-2 alkyl, fluorine, chlorine, C1-2 alkoxy and trifluoromethyl, provided that no more than two of R2, R3 and R4 are other than hydrogen.Also provided are pharmaceutical compositions containing the compounds and their use in medicine, and in particular in the treatment of cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.