Compounds binding to the bacterial beta ring
US9133240B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | Apr 13, 2012 |
| Grant date | Sep 15, 2015 |
| Priority date | — |
| Expiry date | Apr 13, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds which bind to the hydrophobic pocket of the β clamp, i.e., to the surface of the β ring with which said protein interacts with other proteins of the bacterial replication complex during DNA replication. These compounds are derived from the acetylated peptide AcQLDLF (P6) to improve their affinity to their target.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.