Differentiation of human embryonic stem cells
US9133439B2 · kind B2 · utility
17Cited by
75References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 16, 2010 |
| Grant date | Sep 15, 2015 |
| Priority date | — |
| Expiry date | Nov 20, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2506/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides methods to promote the differentiation of pluripotent stem cells into insulin producing cells. In particular, the present invention provides a method to increase the expression of NGN3 and NKX6.1 in populations of cells expressing markers characteristic of the pancreatic endocrine lineage.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.