Patent · US Active

Screening strategies for the identification of binders

US9133500B2 · kind B2 · utility

2Cited by

2References

9Claims

0Family size

Assignee

MorphoSys A6 · DE

Inventors

Christian Frisch · Planegg, DE
Achim Knappik · Gräfelfing, DE
Alex Strongin · San Diego, US
Sergey A. Shiryaev · Moskovskiy, RU

Key dates

Filing date	Aug 6, 2010
Grant date	Sep 15, 2015
Priority date	—
Expiry date	Aug 25, 2030

Classification

Technology area (CPC G)Physics
CPC primaryG01N2500/04
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention discloses novel screening strategies for the identification of binders that target the active site of enzymatic antigens. The present invention also discloses antigen-binding moieties which bind to the NS2B-NS3 Proteinase of West Nile Virus, in particular binders which bind to the active site, thereby inhibiting the enzymatic activity of the proteinase. The antigen-binding moieties of the present invention have numerous therapeutic and diagnostic applications.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.