Compositions, methods, systems and kits for target nucleic acid enrichment
US9133510B2 · kind B2 · utility
57Cited by
1References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 15, 2013 |
| Grant date | Sep 15, 2015 |
| Priority date | — |
| Expiry date | Dec 21, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6853
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides methods, compositions, kits, systems and apparatus that are useful for isolating nucleic acid molecules from a sample. In particular, the methods generally relate to normalizing the concentration of target nucleic acid molecules from a sample. In one aspect, the invention relates to purifying a primer extension product from a primer extension reaction mixture. In some aspects, nucleic acid molecules obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.