Methods of treatment of histamine H-4 receptor-related pruritus
US9138431B2 · kind B2 · utility
10Cited by
8References
6Claims
0Family size
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Key dates
| Filing date | Aug 6, 2013 |
| Grant date | Sep 22, 2015 |
| Priority date | — |
| Expiry date | Aug 6, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The methods disclosed herein relate to the treatment of histamine H-4—related pruritus, by administering a histamine H-4 receptor inverse agonist that selectively accumulates at the biophases of the disorders, specifically RS-norketotifen or a pharmaceutically acceptable salt thereof. Potentiated antipruritic activity by simultaneous inhibition of histamine H-1 receptors and histamine H-4 receptors are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.