Formulations for the treatment of diabetes
US9138479B2 · kind B2 · utility
9Cited by
37References
34Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 31, 2012 |
| Grant date | Sep 22, 2015 |
| Priority date | — |
| Expiry date | Oct 31, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a formulation for parenteral administration comprising insulin that comprises a pH memory between 1 to 4 or between 6 to 8 and an aprotic polar solvent, wherein the insulin is solubilized in the aprotic polar solvent, wherein the solubilized insulin comprises stable monomeric or dimeric forms of insulin or mixtures thereof, and wherein the water content of the formulation is equal to or less than 15% w/v.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.