Closed vial fill system for aseptic dispensing

US9139316B2 · kind B2 · utility

Assignee

• Cardinal Health 414, LLC · US

Inventors

• Mehmet Husnu · Phoenix, US
• Dennis Eshima · Phoenix, US
• Derrick Alcaide · Los Angeles, US
• Scott N. Danhof · Plain City, US
• Jim Gleeson · Columbus, US
• Eric Hassenpflug · Westerville, US
• Jim Prescott · Columbus, US

Key dates

• Filing date: Dec 28, 2011
• Grant date: Sep 22, 2015
• Expiry date: May 9, 2033

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B65B37/06
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A closed path vial fill system includes a bulk product vial, a peristaltic pump operated by a stepper motor, a dispensing manifold assembly to which may be coupled at least one final product vial, an optional quality check station, and an optional waste collection system. A concentration, activity, and volume (CAV) sensor may be incorporated into the system to receive a radiopharmaceutical product directly from a synthesizing unit. A control system may be integrated into the system to provide automated control of various aspects of the radiopharmaceutical dispensing process. The system is used to aseptically dispense finished radiopharmaceuticals into receiving vessels, such as a Quality Control vial, a sterility vial, and/or final product vials, while providing users an efficient means for removing and discarding contaminated disposable components.