Organonitro thioether compounds and medical uses thereof
US9139519B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 18, 2012 |
| Grant date | Sep 22, 2015 |
| Priority date | — |
| Expiry date | May 18, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D205/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides organonitro thioether compounds, compositions containing such compounds, isolated organonitro thioether compounds and methods for using such compounds and compositions to treat cancer in a patient. Exemplary organonitro thioether compounds described herein include 2-(3,3-dinitroazetidin-1-yl)-2-oxoethyl thioethers and variants thereof. Another aspect of the invention provides a pharmaceutical composition, comprising a pharmaceutically acceptable carrier and an organonitro thioether compound described herein, such as a compound of Formula I or II. Another aspect of the invention provides a method of treating cancer in a patient. The method comprises administering to a patient in need thereof a therapeutically effective amount of an organonitro thioether compound described herein, such as a compound of Formula I or II, to treat the cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.