Patent · US Active

2-benzyl, 3-(pyrimidin-2-yl) substituted pyrazoles useful as sGC stimulators

US9139564B2 · kind B2 · utility

11Cited by

7References

6Claims

0Family size

Assignee

IRONWOOD PHARMACEUTICALS, INC. · US

Inventors

Charles Kim · Cambridge, US
Takashi Nakai · Newton, US
Joel Moore · Lexington, US
Nicholas Robert Perl · Somerville, US
G-Yoon Jamie Im · Cambridge, US
Timothy Claude Barden · Salem, US
Rajesh R. Iyengar · Newton, US
Daniel P. Zimmer · Somerville, US
Angelika Fretzen · Somerville, US
Paul Allan Renhowe · Sudbury, US

Key dates

Filing date	Dec 26, 2012
Grant date	Sep 22, 2015
Priority date	—
Expiry date	Dec 26, 2032

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compound of Table I are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.