Patent · US Active

Controlled tunnel gap device for sequencing polymers

US9140682B2 · kind B2 · utility

27Cited by

1References

15Claims

0Family size

Assignee

ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · US

Inventors

Stuart Lindsay · Tempe, US
Shuai Chang · Seattle, US
Jin He · Plano, US
Peiming Zhang · Gilbert, US
Shuo Huang · Los Gatos, US

Key dates

Filing date	Jan 31, 2011
Grant date	Sep 22, 2015
Priority date	—
Expiry date	Dec 14, 2031

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/143333
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention includes compositions, devices, and methods for analyzing a polymer and/or polymer unit. The polymer may be a homo or hetero-polymer such as DNA, RNA, a polysaccharide, or a peptide. The device includes electrodes that form a tunnel gap through which the polymer can pass. The electrodes are functionalized with a reagent attached thereto, and the reagent is capable of forming a transient bond to a polymer unit. When the transient bond forms between the reagent and the unit, a detectable signal is generated and used to analyze the polymer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.