Patent · US Active

Device to expose cells to fluid shear forces and associated systems and methods

US9140684B2 · kind B2 · utility

2Cited by

8References

8Claims

0Family size

Assignee

University of Washington through its Center for Commercialization · US

Inventors

Nathan J. Sniadecki · Seattle, US
Lucas Ting · Seattle, US

Key dates

Filing date	Oct 29, 2012
Grant date	Sep 22, 2015
Priority date	—
Expiry date	Nov 9, 2032

Classification

Technology area (CPC G)Physics
CPC primaryG01N2015/1006
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present technology relates generally to devices to expose cells to fluid shear forces and associated systems and methods. In particular, several embodiments are directed toward devices to expose cells to fluid shear forces in order to measure changes in internal cell forces. In some embodiments, a fluidic device includes a flow unit configured to induce fluid flow through the device. The device further includes a fluid channel configured to accept a biological sample dispersed on an array of flexible structures. The flow unit can be configured to induce disturbed and/or laminar flow in the fluid channel. The device can further include optical or magnetic detection means configured to measure a degree of deflection of one or more flexible structures in the array.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.