Method and device for measuring dissolved substances in human or animal intraocular fluid
US9144400B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Apr 2, 2014 |
| Grant date | Sep 29, 2015 |
| Priority date | — |
| Expiry date | Apr 2, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B5/14558
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Non-invasive optical measurement of glucose and other dissolved substances in human or animal intraocular fluid. A method takes advantage of the fact that the wave dependence of optical activity is fundamentally different from corneal birefringence. The optical activity of substances dissolved in the intraocular fluid, such as glucose, lactate, ascorbic acid or amino acids, is scaled as a first approximation with the reciprocal value of the wavelength square. In contrast, corneal birefringence is scaled with the reciprocal value of the wavelength and therefore behaves considerably different from the optical activity. For the method according to the invention, a physical model is used, which describes the influence on the polarization of measurement radiation by the components of the eye, particularly by the intraocular fluid and the cornea.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.