Patent · US Active

Cell separation apparatus and methods of use

US9144583B2 · kind B2 · utility

6Cited by
14References
49Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 23, 2007
Grant dateSep 29, 2015
Priority date
Expiry dateApr 20, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12M45/09
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides automated devices for use in supporting various cell therapies and tissue engineering methods. The present invention provides an automated cell separation apparatus capable of separating cells from a tissue sample for use in cell therapies and/or tissue engineering. The cell separation apparatus can be used in combination with complementary devices such as cell collection device and/or a sodding apparatus to support various therapies. The automated apparatus includes media and tissue dissociating chemical reservoirs, filters, a cell separator and a perfusion flow loop through a graft chamber which supports a graft substrate or other endovascular device. The present invention further provides methods for using the tissue grafts and cell samples prepared by the devices described herein in a multitude of therapies including revascularization, regeneration and reconstruction of tissues and organs, as well as treatment and prevention of diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.