Preparation method of human metabolites of simvastatin or lovastatin using bacterial cytochrome P450 and composition therefor
US9145571B2 · kind B2 · utility
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Key dates
| Filing date | Aug 24, 2010 |
| Grant date | Sep 29, 2015 |
| Priority date | — |
| Expiry date | Apr 22, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y114/14001
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of producing human metabolites of simvastatin or lovastatin, and more particularly, a method of producing human metabolites of simvastatin and lovastatin by using bacterial cytochrome P450 BM3(CYP102A1) or mutants thereof, and a composition and kit therefor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.