Detecting molecular interactions by fluorescence resonance energy transfer on a solid-phase support
US9146233B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 13, 2007 |
| Grant date | Sep 29, 2015 |
| Priority date | — |
| Expiry date | Mar 30, 2029 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present disclosure features a variety of compositions, kits, and methods that are useful for, inter alia, detecting and/or analyzing an interaction between two molecules, a target molecule and a target-specific binding agent which can be, e.g., proteins, nucleic acids, saccharides or polysaccharides, small molecules, or combinations of any of the foregoing. The compositions, kits, and methods can also be used, e.g., to detect the presence or absence of an enzymatic activity (e.g., a kinase activity, a protease activity, or a phosphatase activity) in a sample; to identify a compound that modulates an interaction between two molecules; or to identify compounds that modulate the activity of an enzyme.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.