Low impurity content caspofungin preparation, method for preparing same, and use thereof
US9149502B2 · kind B2 · utility
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27Claims
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Key dates
| Filing date | Sep 25, 2012 |
| Grant date | Oct 6, 2015 |
| Priority date | — |
| Expiry date | Sep 25, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K7/56
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a low impurity content caspofungin pharmaceutical composition and a method for preparing the low impurity content caspofungin pharmaceutical composition. The caspofungin pharmaceutical composition comprises the compound of formula I and/or a pharmaceutically acceptable salt thereof, in combination with a saccharide protective agent(s) and an amino acid(s). The caspofungin pharmaceutical composition is prepared by dissolving the saccharide protective agent and the amino acid into water or a suitable buffer solution; adding the caspofungin compound and dissolving it; filtering the solution and lyophilizing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.