Polymer conjugate of folic acid or folic acid derivative
US9149540B2 · kind B2 · utility
3Cited by
41References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 28, 2009 |
| Grant date | Oct 6, 2015 |
| Priority date | — |
| Expiry date | Apr 28, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G69/48
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a polymer conjugate of folic acid or a folic acid derivative, wherein an amide bond is not used. The compound has chemical stability and adequate drug release rate in the living organism. Specifically disclosed is a polymer conjugate of folic acid or a folic acid derivative, wherein a substituent represented by formula (I) is bonded to a carboxy group of a block copolymer which is composed of a polyethylene glycol and a polymer having a carboxy group in a side chain, or a pharmacologically acceptable salt thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.