Thermal cycler with vapor chamber for rapid temperature changes
US9149809B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 1, 2012 |
| Grant date | Oct 6, 2015 |
| Priority date | — |
| Expiry date | Nov 14, 2032 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2300/1855
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Rapid and uniform temperature changes in the wells of a microplate or any thin-walled plate that contains an array of reaction wells or sample receptacles are achieved by the use of heating and cooling elements with a vapor chamber interposed between such elements and the microplate. The upper surface of the vapor chamber and the underside of the sample plate in certain embodiments are complementary in shape, i.e., they have identical but oppositely directed contours in the areas around each of the sample receptacles, to provide continuous surface contact along the surface of each receptacle. In other embodiments, an intermediary plate is placed between the vapor chamber and the well plate, with the top surface of the intermediary plate being complementary in shape to the underside of the well plate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.