Patent · US Active

Process for the preparation of 4-amino-1-((1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-hydroxymethyl-cyclopent-2-enyl)-1H-pyrimidin-2-one

US9150520B2 · kind B2 · utility

4Cited by

1References

29Claims

0Family size

Assignee

REXAHN PHARMACEUTICALS, INC. · US

Inventors

Haifeng Yin · Shanghai, CN
Deog Joong Kim · Rockville, US
Eliezer Falb · Givatayim, IL
Leigh Andre Pearcey · Biggenden, AU
Jonathan Cummins · Biggenden, AU
Petra Dieterich · Abingdon, GB
Jean-Francois Carniaux · Abington, GB
Yi Wang · Chester Springs, US
Vikram Purohit · Downingtown, US

Key dates

Filing date	Mar 17, 2014
Grant date	Oct 6, 2015
Priority date	—
Expiry date	Mar 17, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F7/1892
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Processes for the preparation of 4-amino-1-((1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-hydroxymethyl-cyclopent-2-enyl)-1H-pyrimidin-2-one (13, RX-3117) and its intermediates are described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.