Patent · US Active

Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as parp and tubulin polymerization inhibitors

US9150540B2 · kind B2 · utility

1Cited by
14References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 14, 2014
Grant dateOct 6, 2015
Priority date
Expiry dateOct 14, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D221/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides compounds of formula (I), their use as inhibitors of tubulin polymerization and their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I)wherein R1, R2, R3, R4, R5, R6, R7 and Y have defined meanings.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.