Biological inhibitors of ROR1 capable of inducing cell death

US9150647B2 · kind B2 · utility

Assignee

• Kancera AB · SE

Inventors

• Hakan Mellstedt · Stockholm, SE
• Hodjattallah Rabbani · Stockholm, SE
• Ingrid Teige · Lund, SE

Key dates

• Filing date: Dec 10, 2010
• Grant date: Oct 6, 2015
• Expiry date: Dec 10, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2310/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to antibodies and siRNA molecules for inducing cell death by the specific binding of ROR1, domains thereof of nucleotide molecules encoding ROR1. There are also provided methods involving and uses of the antibodies and siRNA molecules of the invention.