Differentiation of human embryonic stem cells
US9150833B2 · kind B2 · utility
3Cited by
74References
14Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 16, 2010 |
| Grant date | Oct 6, 2015 |
| Priority date | — |
| Expiry date | Jun 22, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/90
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides methods to promote the differentiation of pluripotent stem cells into insulin producing cells. In particular, the present invention provides a method to produce cells expressing markers characteristic of the pancreatic endocrine lineage that co-express NKX6.1 and insulin and minimal amounts of glucagon.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.