Lyase enzymes, nucleic acids encoding them and methods for making and using them
US9150845B2 · kind B2 · utility
3Cited by
2References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 30, 2013 |
| Grant date | Oct 6, 2015 |
| Priority date | — |
| Expiry date | Aug 30, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y403/01023
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention provides polypeptides having lyase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides having ammonia lyase activity, e.g., phenylalanine ammonia lyase, tyrosine ammonia lyase and/or histidine ammonia lyase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.