Targeted alteration of DNA
US9150854B2 · kind B2 · utility
0Cited by
7References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 25, 2011 |
| Grant date | Oct 6, 2015 |
| Priority date | — |
| Expiry date | May 8, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/1082
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The current invention relates to a method for targeted alteration of acceptor DNA, for example duplex acceptor DNA. The method comprises the use of an oligonucleotide having at least one mismatch relative to the targeted (duplex) acceptor DNA. The mismatch is located at specific positions within said oligonucleotide. Also provided is a kit that comprises instructions for performing the method according to the inventions, and in a preferred embodiment, comprises an oligonucleotide suitable for use in the method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.