Identification of compounds modifying a cellular response
US9150899B2 · kind B2 · utility
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7Claims
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Assignee
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Key dates
| Filing date | Apr 6, 2012 |
| Grant date | Oct 6, 2015 |
| Priority date | — |
| Expiry date | May 16, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to methods for identifying compounds capable of modulating a cellular response. The methods involve attaching living cells to solid supports comprising a library of test compounds. The test compounds are linked to the solid support via cleavable linkers and may thus be released from the solid supports. Solid supports comprising cells, wherein the cellular response of interest has been modulated are selected and the test compound of the solid support can then be identified. The cellular response may for example be changes in complex formation between proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.