Process for the preparation of pharmaceutical suspensions for inhalation
US9155700B2 · kind B2 · utility
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12References
5Claims
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Key dates
| Filing date | Dec 21, 2011 |
| Grant date | Oct 13, 2015 |
| Priority date | — |
| Expiry date | Dec 21, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P29/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Process for preparing sterile suspensions for inhalation comprising an active ingredient insoluble in water and wherein at least 80% of the particles of said active ingredient have a diameter between 3 and 5 μm, comprising the following stages: dissolving the active ingredient in the minimum quantity of an alcoholic solvent, optionally in the presence of a polyol and adding at least one surfactant, filtering the solution obtained in the previous stage through a sterilizing filter, adding the solution from stage (b) to sterile water under sonication to directly obtain a suspension wherein the particles have a reduced diameter.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.