Patent · US Active

Pharmaceutical composition and method for regenerating myofibers in the treatment of muscle injuries

US9155744B2 · kind B2 · utility

1Cited by

3References

7Claims

0Family size

Assignee

Lead Billion Limited · CN

Inventors

Ming Li · Hong Kong, CN
Lei Cheng · Kunshan, CN
Hong Liu · Shanghai, CN

Key dates

Filing date	Oct 27, 2006
Grant date	Oct 13, 2015
Priority date	—
Expiry date	May 17, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C62/32
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A pharmaceutical composition and method for regenerating cardiomyocytes in treating or repairing heart muscle damages or injuries caused by an ischemic disease. The pharmaceutical composition contains an active ingredient compound with a backbone structure of Formula (I). The active ingredient compound is capable of (a) increasing viability of myogenic precursor cells to enable said precursor cells to survive through an absolute ischemic period; (b) reconstituting a damaged blood supply network in said heart region where said injured muscle is located; and (c) enhancing cardiomyogenic differentiation efficiency of said precursor cells down cardiac linage, said steps being performed simultaneously or in any particular order.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.