Separation medium for chromatography of various biomolecules
US9155980B2 · kind B2 · utility
12Cited by
3References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 20, 2013 |
| Grant date | Oct 13, 2015 |
| Priority date | — |
| Expiry date | Dec 12, 2033 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D15/166
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present invention relates to a separation medium, comprising an inner core of a porous material provided with charged ligands, and an outer lid comprising a porous material provided with charged ligands, wherein the charge of the ligands in the inner core is opposite that of the charge of the ligands in the lid. The present invention also relates to a method for biomolecule separation comprising applying a sample to the above separation medium, wherein large molecules are prevented from entering the medium by charge repulsion from the medium and small molecules are captured in the inner core.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.