TRPV3 modulators

US9156788B2 · kind B2 · utility

Assignee

• Abb Vie Inc. · US

Inventors

• Erol K. Bayburt · Gurnee, US
• Bruce Clapham · Lindenhurst, US
• Phil B. Cox · Grayslake, US
• Jerome F. Daanen · Racine, US
• Arthur Gomtsyan · Vernon Hills, US
• Michael E. Kort · Lake Bluff, US
• Philip R. Kym · Libertyville, US
• Eric A. Voight · Pleasant Prairie, US

Key dates

• Filing date: Feb 7, 2013
• Grant date: Oct 13, 2015
• Expiry date: Jun 2, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disclosed herein are modulators of TRPV3 of formula (I)wherein G1, X1, X2, X3, X4, X5, G2, Z1, Ra, Rb, u, and p are as defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also presented.