CH2 domain template molecules derived from rational grafting of donor loops onto CH2 scaffolds
US9156917B2 · kind B2 · utility
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Key dates
| Filing date | Feb 10, 2012 |
| Grant date | Oct 13, 2015 |
| Priority date | — |
| Expiry date | Feb 10, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/94
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Novel CH2 domain template molecules wherein donor loops from a database of domains are transferred to a CH2 domain scaffold. At least one or up to three loops from a donor are transferred to the CH2 domain. The donor loops may be chosen based on length, e.g., the donor loop may have a length that is similar to that of a structural loop in the CH2 domain scaffold.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.