MicroRNA compounds and methods for modulating miR-122
US9157083B2 · kind B2 · utility
7Cited by
14References
20Claims
0Family size
Assignee
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Key dates
| Filing date | Dec 19, 2014 |
| Grant date | Oct 13, 2015 |
| Priority date | — |
| Expiry date | Dec 19, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/31
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are compositions and methods for the inhibition of miR-122 activity. The compositions have certain nucleoside modifications that yield potent inhibitors of miR-122 activity. The compounds may comprise conjugates to facilitate delivery to the liver. The compositions may be administered to subjects infected with hepatitis C virus, as a treatment for hepatitis C virus and related conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.